DNA is an important tool used to exonerate individuals who were wrongfully convicted and uncover weaknesses in our criminal legal system. When DNA was first used in criminal cases, large amounts of biological evidence were required to create DNA profiles. Now, DNA techniques have become far more sensitive, which allows for the collection of DNA from trace amounts of biological evidence. This increased sensitivity has enabled scientists to analyze compound samples that involve multiple contributors. It has also created new issues. This panel will provide an overview of various recent advances in DNA testing, highlight complications that these new technologies may present, and discuss how more complex DNA techniques may assist in the investigation and litigation of wrongful convictions. This session is intended for attendees who have a basic understanding of DNA and are hoping to jump into advanced areas of DNA testing.